As the publisher of Skeptic magazine I am often asked what I mean by skepticism, and if I'm skeptical of everything or if I actually believe anything. Skepticism is not a position that you stake out ahead of time and stick to no matter what.
Consider global warming: Are you a global warming skeptic? Or are you skeptical of the global warming skeptics? In this case, I used to be a global warming skeptic, but now I'm skeptical of the global warming skeptics, which makes me a global warming believer based on the facts as I understand them at the moment. The "at the moment" part is what makes conclusions in science and skepticism provisional.
Thus, science and skepticism are synonymous, and in both cases it's okay to change your mind if the evidence changes. It all comes down to this question: What are the facts in support or against a particular claim?
There is also a popular notion that skeptics are closed-minded. Some even call us cynics. In principle, skeptics are neither closed-minded nor cynical. We are curious but cautious.