The group, who reported their progress in the journal Nature Communications, used induced pluripotent stem cells (iPS cells) to accomplish the feat. These mature human cells are first "reprogrammed" to an embryonic state, before being spurred to develop into a specialized type of cell. In this instance, iPS cells derived from human skin were induced to become multipotential cardiovascular progenitor (MCP) cells — basically heart cells that can further differentiate into three varieties of highly specialized cells required for cardiovascular function.