New blood ‘recharges old brain’, mouse study suggests


Researchers in the US say they might have discovered how to combat and even reverse some processes of ageing, at least in mice.

Injecting the blood of young mice into older rodents boosted their brainpower, a study found.

Scientists at Stanford University plan to carry out trials in people in the hope that new treatments for dementia can be developed.

A UK dementia research charity said the human significance was unknown.

In the study, published in Nature Medicine, mice aged 18 months were given injections of the fluid part of blood (plasma) taken from mice aged three months.

The injected mice performed better on memory tests than mice of the same age that had not been given blood plasma.

"There are factors present in blood from young mice that can recharge an old mouse's brain so that it functions more like a younger one," said Dr Tony Wyss-Coray of Stanford University School of Medicine.

"We're working intensively to find out what those factors might be and from exactly which tissues they originate."

He said it was not known whether the same was true in humans, but a clinical trial was planned.

Written By: Helen Briggs
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  1. Gives the expression “injecting fresh blood into a project” a whole new meaning right? Just one problem, blood banks are always short of blood essential for life-saving surgery. How do we reconcile that fact with people who want to use that precious blood just to feel younger (or smarter)?

  2. Maybe they should just check with Lance Armstrong.

    He’s been running human trials for many years.
    Technique involves working intensively to develop techniques that prevent anyone from finding out what the factors might be. If it’s possible to identify the factors and to easily test for them then the benefits are lost.

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