Dissolving stent for heart arteries passes first large test

Oct 22, 2015

Weinberg-Clark Photography/Abbott via AP

By Marilynn Marchione

Now you see it, now you don’t. A new type of heart stent that works like dissolving stitches, slowly going away after it has done its job, passed its first major test in a large study, doctors said Monday.

Abbott Vascular’s dissolving Absorb stent performed as well as a conventional stent in the one-year study, but the fact it did not prove superior led some experts to be wary.

Still, the results on this and other novel currently in testing are fueling hope for a new generation of these devices, used on about 850,000 heart disease patients each year in the United States alone.

Stents are tiny mesh cages that keep blood vessels from reclogging after an artery-opening angioplasty procedure. The ones available now in the U.S. are permanent implants made of metal, usually coated with a material that oozes medicine, but they sometimes cause inflammation and other problems years down the road.

The Absorb stent, already sold in Europe, is made of a degradable material that’s designed to stay intact and release medicine for a year, then break down over the next two years.

“It holds the artery open long enough for the artery to heal,” then completely goes away, said one study leader, Dr. Dean Kereiakes of Christ Heart and Vascular Center in Cincinnati. “It can return the artery to its normal, natural structure and function.”

The study involved about 2,000 patients with chest pain due to one or two clogged arteries, and was aimed at winning Food and Drug Administration approval to sell Absorb in the U.S.


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